In this study, DFNB1 children who use cochlear implants show greater gains in expressive language than non-DFNB1 children,

independent of residual hearing, age at implantation, and duration of implant use.”
“Pneumocephalus is an exceedingly rare complication associated with neurological deficit in cases of frontoethmoid osteoma. The overarching management strategy for affected patients remains undefined. We describe the case of a 61-year-old female patient presenting with frontoethmoid selleck inhibitor osteoma manifesting as profound intraparenchymal pneumocephalus and associated neurological deficit, treated through a minimally invasive combined surgical strategy involving image-guided burr hole decompression of the pneumocephalus followed by transnasal endoscopic removal of the tumor. Using this approach, the patient rapidly recovered full neurologic function. We review the existing literature and, given the likely intraparenchymal location of pneumocephalus associated with these lesions with the potential of rapid clinical deterioration, recommend aggressive surgical management. Although these lesions can be removed from a purely endoscopic approach, we recommend

burr-hole decompression of the pneumocephalus as an adjunct to ensure prompt resolution of the neurologic symptoms.”
“Background: Late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) is frequently used to evaluate myocardial viability, estimate Selleckchem KU-55933 total infarct size and transmurality,

but is not always straightforward is and contraindicated in patients with renal failure LDC000067 because of the risk of nephrogenic systemic fibrosis. T2- and T1-weighted CMR alone is however relatively insensitive to chronic myocardial infarction (MI) in the absence of a contrast agent. The objective of this manuscript is to explore T1 rho-weighted rotating frame CMR techniques for infarct characterization without contrast agents. We hypothesize that T1 rho MR accurately measures infarct size in chronic MI on account of a large change in T1 rho relaxation time between scar and myocardium.

Methods: 7Yorkshire swine underwent CMR at 8 weeks post-surgical induction of apical or posterolateral myocardial infarction. Late gadolinium enhanced and T1 rho CMR were performed at high resolution to visualize MI. T1 rho-weighted imaging was performed with a B-1 = 500 Hz spin lock pulse on a 3 T clinical MR scanner. Following sacrifice, the heart was excised and infarct size was calculated by optical planimetry. Infarct size was calculated for all three methods (LGE, T1 rho and planimetry) and statistical analysis was performed. T1 rho relaxation time maps were computed from multiple T1 rho-weighted images at varying spin lock duration.

Results: Mean infarct contrast-to-noise ratio (CNR) in LGE and T1 rho CMR was 2.8 +/- 0.1 and 2.7 +/- 0.1.