5%, Group B 2/37, 5.4%) were not different

between group A and group B. Conclusion: Tumor size was difficult factor to procedure colorectal ESD. In case of large size tumor, more caution is needed during submucosal dissection. Key Word(s): 1. ESD; 2. colon; Presenting Author: LIJUAN QIAN Additional Authors: RUIHUA SHI Corresponding Author: LIJUAN QIAN, RUIHUA SHI Affiliations: the First Affiliated Hospital of Soochow University; the First Affiliated Hospital of Nanjing Medical University Objective: To investigate the risk factors for the development of proximal tissue hyperplasia after stenting in patients with malignant and benign esophageal strictures. Methods: Consecutive patients of malignant and benign esophageal strictures who received esophageal stents were enrolled in this retrospective analysis. Endoscopy follow-up was performed one month after stenting to evaluate the severity of proximal Selleckchem Everolimus tissue hyperplasia. We evaluated the significance of patient age, sex, stent

diameter, and stent length as factors contributing to the development of proximal tissue hyperplasia. Results: A total of 168 patients were included. Technical success was achieved in all patients. Different GSK458 datasheet severity of tissue hyperplasia occurred in all patients one month after stenting. Stent diameter in patients of benign strictures was larger than those of malignant strictures (20.5 ± 2.9 mm versus 18.3 ± 2.1 mm, P < 0.001). Regression analysis revealed that tissue hyperplasia was significantly Celecoxib more severe in patients with large stent diameter (Odds Ratio 1.202, 95%CI 1.045–1.383, P = 0.010). No significant relationship was identified between the severity of tissue hyperplasia and age, sex, or stent length. Conclusion: Patients of benign esophageal strictures usually insert stents with large diameter to expand the stricture effectively. Large stent diameter is important factors that contribute to severe tissue hyperplasia after esophageal stenting. Key Word(s): 1. esophageal

stent; 2. tissue hyperplasia; 3. esophageal stricture; Presenting Author: LIJUAN QIAN Additional Authors: RUIHUA SHI Corresponding Author: RUIHUA SHI Affiliations: he First Affiliated Hospital of Soochow University; the First Affiliated Hospital of Nanjing Medical University Objective: To compare the efficacy and safety of pneumatic dilation with stenting, a less reported modality for the treatment of achalasia. Methods: Patients with newly diagnosed achalasia were allocated for treatment with pneumatic dilation or stenting. Clinical symptoms were assessed with the use of Eckardt score. Timed barium esophagram and esophageal manometry were performed at pre-treatment and post-treatment follow-up visits. Data such as patient demographics and complications were collected. The Eckardt score drop to ≤3 was defined as treatment success. Results: A total of 151 patients were enrolled for treatment with pneumatic dilation (N = 76) or stenting (N = 75).