Objective. To determine whether a silicone material can be used as an intervertebral disc thermal phantom for evaluating thermal distributions of intradiscal electrothermal therapies and for reducing the need for cadaver and animal studies.
Summary of Background Data. Studies mapping click here thermal profiles of intradiscal heating therapies have been performed in cadavers and animal models. These studies are expensive, require special facilities and institutional reviews, and are susceptible to intercadaver and/or interanimal variation. A search of published data yielded no proposed thermal phantoms of the intervertebral
disc.
Methods. The thermal conductivity of a silicone material was measured and compared with
that of an intervertebral disc. Thermal distributions were mapped in the material during the IDET procedure and compared with the distributions seen in cadaver studies. Logarithmic GNS-1480 molecular weight regression was performed to predict temperatures at certain distances from the IDET catheter. Mapping and regression were also performed for a decompression catheter.
Results. The thermal conductivity of the silicone material, 0.587 W/m.degrees C, was similar to that previously reported for the intervertebral disc, 0.595 W/m.degrees C. Thermal distributions during the IDET procedure were comparable with those seen in previous cadaver studies. Logarithmic regression analysis predicted temperatures greater than 42 degrees C and 60 degrees C at distances of 14.10 and 2.31 mm, respectively, for the IDET catheter. These distances
were 12.98 and 3.30 mm, respectively, for the decompression catheter.
Conclusion. The silicone material has a thermal conductivity similar to that of intervertebral disc. Temperature distributions AZD4547 research buy in the material during IDET treatment are similar to that seen in cadaver studies. The material provides an alternative to cadaver and animal studies when determining thermal distributions of intradiscal electrothermal therapies.”
“The other articles in this supplement to the Journal presented the science behind 4 nutrient profiling systems currently available in the US marketplace that cross manufacturers and apply to multiple food categories and have considered their value as tools to promote positive behavior change in American consumers. This article discusses these nutrient profiling systems in terms of the consumer’s understanding of science, familiarity with label messaging, and potential to facilitate healthy food decisions. Am J Clin Nutr 2010;91(suppl):1116S-7S.”
“Study Design. Human cadaveric biomechanical study of indentation tests on the thoracolumbar vertebral endplates.
Objective. To map the strength profile of the thoracolumbar endplates using indentation testing, and to document any changes in this profile with vertebral level.
Summary of Background Data.