Patient demographics including self-reported ethnicity, disease characteristics, highest educational level, Crohn’s and Colitis Australia (CCA) membership, and information resource use
were recorded. The 24-item validated CCKnow questionnaire CP673451 was used to assess IBD-specific knowledge.1 Results: Of 114 IBD patients, 52.6% Middle Eastern and 57.8% Caucasian patients were female (P = 0.57). Middle Eastern and Caucasian patients were similar in age (median 35.0 vs. 34.0 years; P = 0.90), age-at-diagnosis (median 28.0 vs. 24.0 years; P = 0.50) and disease duration (median 8.0 vs. 7.0 years; P = 0.92). Forty Middle Eastern (70.2%) and 42 (73.7%) Caucasian patients had Crohn’s disease (P = 0.67). Disease phenotype, behaviour and activity (P = 0.56) were similar in both groups with the exception of perianal disease which was found in 42.5% Middle Eastern and 22.4% Caucasians respectively (P = 0.04). The mean and median CCKNOW score were significantly lower at 7.54 +/− 4.04 and 7.00 (IQR: 7) in Middle Eastern patients NVP-BGJ398 in comparison with Caucasian patients where scores of 10.98 +/− 5.06 and 11.00 (IQR: 8) respectively were found (P < 0.001). Knowledge in 26 (45.6%) first generation migrants (mean 6.08 +/− 3.67) was significantly lower (P = 0.01) than in
31 (54%) second generation migrants (mean 8.77 +/− 3.98). A significant knowledge difference was maintained when comparing 2nd generation migrants alone with Caucasian patients (P = 0.04). CCA membership was not associated with better knowledge (P = 0.09). Multiple linear regression analysis revealed that Caucasian ethnicity (ß = 0.273, P = 0.001)
and internet use for IBD-related health information (ß = 0.378, P < 0.001) were independent predictors of better knowledge. Conclusions: IBD-related knowledge was poor in both Middle Eastern and Caucasian IBD patients. A CCKnow knowledge deficit gradient exists such that knowledge is lowest in first generation migrants, intermediate in second 上海皓元医药股份有限公司 generation migrants and highest in Caucasians. This knowledge deficit may represent an unmet need in Middle Eastern IBD patients with potential to impact on their ongoing care. 1. Eaden JA, Abrams K, Mayberry JF. The Crohn’s and Colitis Knowledge Score: a test for measuring patient knowledge in inflammatory bowel disease. Am J Gastroenterol. 1999;94:3560–3566. RO BUTCHER,1,2 C CORTE,1 G BARR,1 G CHAPMAN,1 J COWLISHAW,1 DB JONES,1 P KATELARIS,1 C MCDONALD,1 J MCLAUGHLIN,2 SS CAMPBELL,2 RW LEONG1 1Gastroenterology and Liver Services, Concord Hospital and Bankstown Hospital, Sydney, Australia, 2Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK Background and Aims: Complementary and alternative medicine (CAM) use in inflammatory bowel disease (IBD) is common. CAM use may differ among different ethnic groups.