stolonifer possesses significant herbicidal, cytotoxic and antifungal properties. Isolation and characterization is required for structural elucidation of its bioactive compounds.”
“Objective: To study the perinatal outcome according to whether labor was induced or not, when a low-risk pregnancy reached 41 weeks of gestation. Methods: A quasi-experimental study of 11492 low-risk singleton pregnancies was designed.
A total of 1,721 patients (15.0%) women met the study criteria, were informed about the risks and benefits and gave check details their informed consent, of whom 629 (36.5%) were planned for induction soon after the 41 weeks (287-289 days). Results: An intention-to-treat analysis was performed. The proportion of small-for-gestational age babies was lower in the early-induced labor cohort (10.5% versus 15%; p = 0.008). This cohort showed an increased hospital stay (4.54 versus 3.80 days; p < 0.001), and a higher rate of requiring delivery by caesarean section (31.1% versus 19.8%; p < 0.001), including the need for caesarean Apoptosis Compound Library purchase section for failed
induction (21.8% versus 11%; p < 0.001). Three stillbirths occurred in the group followed expectantly, whereas no stillbirths were seen in the early induction group. Conclusions: Induction of labor for prolonged pregnancy in low-risk patients soon after the 41 weeks, reduces the proportion of small-for-gestational age babies, but increases the mean hospital stay as well as the need for delivery by caesarean section, including that for failed induction.”
“”"Adverse Drug Reactions in General Pediatrics Units of a University Hospital”". Increased adverse drug reactions (ADRs) in the pediatric population are an important factor of admission and extended length of stay. In the present paper the ADR prevalence in pediatric patients hospitalized in general units of a University Hospital is described. A Cohort study, from January 2005 to December 2006, by means of an active search in records of hospitalized children, was carried out; during this period 3,726 patients were assessed. The mean age was 6.4 years old. The ADR prevalence was 8%, being more frequent INCB028050 in males (53%). Vancomycin was
the medicine most correlated with the ADR suspicions (16.2%). The dermatological system was the most affected, corresponding to 35.8%, being skin rash (24%) the most correlated reaction. According to Naranjo algorithm, 71% were classified as probable. Pharmacovigilance is intended to detect ADRs early, and then adopt preventive measures during the utilization of medicines.”
“Purpose: To investigate the cytotoxic and apoptotic activities of Ficus pseudopalma (FP) Blanco leaf extracts against normal human FSE cells and human prostate PRST2 cancer cell line.
Methods: FP leaves were extracted with 95 % ethanol, and partitioned with chloroform, ethylacetate, and water. The presence of terpenoid lupeol and flavonoid quercetin was determined through high performance liquid chromatography (HPLC).