The work was supported by the Oversight Committee for The Evaluation of Metabolic Complications of HAART, a collaborative committee with representation from academic institutions, the European Agency for the valuation of Medicinal Products, the Food and Drug Administration, the patient community, and all pharmaceutical companies with licensed anti-HIV drugs in the US market:

Abbott, Boehringer Ingelheim, Bristol-Myers Squibb, Gilead Sciences, GlaxoSmithKline, Merck, Pfizer, and Hoffman-LaRoche. It was also supported by a grant (CURE/97-46486) from the Health Insurance Fund Council, Amstelveen, the Netherlands, to the AIDS Therapy Evaluation Project Netherlands (ATHENA); by a grant from the Agence Nationale selleck chemical de Recherches sur le SIDA (Action Coordonnée no. 7, Cohortes) to the Aquitaine Cohort. The Australian HIV Observational Database is funded as part of the Asia Pacific HIV Observational NVP-AUY922 mouse Database, a programme of The Foundation for AIDS Research (amfAR). The work was also supported in part by a grant from the US National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) (Grant No. U01-AI069907) and by unconditional grants from Merck Sharp & Dohme, Gilead, Bristol-Myers Squibb, Boehringer Ingelheim, Roche, Pfizer, GlaxoSmithKline and Janssen-Cilag. The National Centre in HIV Epidemiology and Clinical Research is funded by The Australian Government

Department of Health and Ageing, Ixazomib clinical trial and is affiliated with the Faculty of Medicine, The University of New South Wales. In addition, the Barcelona Antiretroviral Surveillance Study (BASS) received grants from the Fondo de Investigación Sanitaria (FIS 99/0887) and Fundación para la Investigación y la Prevención del SIDA en Espanã (FIPSE 3171/00); the Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) received grants from the National Institute of Allergy and Infectious Diseases, National Institutes of Health (grants 5U01AI042170-10 and

5U01AI046362-03); the EuroSIDA study received grants from the BIOMED 1 (CT94-1637) and BIOMED 2 (CT97-2713) programmes and the fifth framework programme (QLK2-2000-00773) of the European Commission and grants from Bristol-Myers Squibb, GlaxoSmithKline, Boehringer Ingelheim and Roche; the Italian Cohort Naïve to Antiretrovirals (ICONA) Foundation received unrestricted educational grants from Abbott, Boehringer Ingelheim, Bristol-Myers Squibb, Gilead, GSK, Pfizer and Janssen-Cilag; and the Swiss HIV Cohort Study (SHCS) received a grant from the Swiss National Science Foundation. Conflicts of interest: The D:A:D collaboration is supported financially by various institutions including all pharmaceutical companies with licensed anti-HIV drugs in the US market: Abbott, Boehringer Ingelheim, Bristol-Myers Squibb, Gilead Sciences, GlaxoSmithKline, Merck, Pfizer and Hoffman-LaRoche.