With the FeCNT probe, no tilt of the probe magnetization could be observed in in-plane fields up to the experimental limit of 230 mT. Due to the large shape anisotropy of the enclosed iron nanowire its direction of magnetization stays mainly oriented along the long axis even in moderate fields that deviate from this easy axis. Consequently, this probe is best suited for MFM measurements in external fields. Doramapimod order (C) 2010 American Institute of Physics. [doi: 10.1063/1.3459879]“
“BACKGROUND: Lung transplant (LTx) candidates are frequently over or underweight.
Few studies have examined recipient weight and outcomes after LTx. The United Network for Organ Sharing (UNOS) database provides an opportunity to examine outcomes related to body mass index (BMI) in a large cohort of LTx patients.
METHODS: The UNOS data set was retrospectively reviewed for 11,411 adult primary LTx patients (1998 to 2008). buy SIS3 Patients were stratified by recipient BMI (kg/m(2)): less than 18.5 (underweight), 18.5 to 24.9 (normal), 25.0 to 29.9 (overweight), more than 30 (obese). All-cause mortality was examined with Cox proportional hazard regression incorporating 15 variables. Survival was modeled using the Kaplan-Meier method.
RESULTS: Of 11,411 recipients, 1,355 (11.9%) were underweight, 4,998 (43.8%) were normal weight, 3,662 (62.1%) were overweight, and 1,396 (12.2%) were obese. During the study,
4,959 patients (43.5%) died. Mortality was significantly different between the strata, with incremental increases in death for each BMI category above or below normal. On multivariable analysis, Selleck AZD1390 BMI strata predicted death compared with normal weight. Risk of death was increased
in recipients who were underweight (hazard ratio [HR], 1.14; 95% confidence interval [CI], 1.03-1.26; p = 0.01), overweight (HR, 1.06; 95% CI, 0.99-1.14; p = 0.1), and obese (HR, 1.16; 95% CI, 1.04-1.28; p = 0.005). Kaplan-Meier modeling showed a significant effect of BMI on survival; however, this effect was no longer significant when first-year deaths were excluded.
CONCLUSIONS: Mortality is higher in underweight, overweight, and obese LTx patients than in normal-weight controls. However, this effect appears to be governed by survival in the first year after LTx. J Heart Lung Transplant 2010;29:1026-33 (C) 2010 International Society for Heart and Lung Transplantation. All rights reserved.”
“Objectives An appraisal of pediatric cancer-specific quality-of-life (QOL) instruments revealed a lack of clarity about what constitutes QOL in this population. This study addresses this concern by identifying the concepts that underpin the construct of QOL as determined by a content analysis of all patient-reported outcome (PRO) instruments used in childhood cancer research.
A systematic review was performed of key databases (i.e., MEDLINE, CINAHL, PsychINFO) to identify studies of QOL in children with cancer.